SmartGene

CRO Services

From Vector to Cell Line, in One Place

A one-stop contract development service on SmartGene's CHO-Speed™ platform, from initial vector construction through to an established high-productivity stable cell line.

Fig. 1
CHO-Speed workflow: gene design, vector cloning, transfection with SGTNase, selection and screening, research cell bank
Fig. 1. From gene design to a research cell bank (RCB) on the one CHO-Speed™ platform. Our own pipeline and external CRO projects run the same process.

Development Workflow

  1. 01

    Gene Design

  2. 02

    Vector Cloning

  3. 03

    Transfection

  4. 04

    Selection & Screening

  5. 05

    Research Cell Bank

Services

Cell Line Development (CLD)

  • Gene design, vector cloning and transfection
  • Stable pool and monoclonal cell line selection
  • Research cell bank (RCB) establishment
  • Expression and stability data package

Molecular Biology Services

  • Cloning and vector construction
  • Codon optimisation
  • Expression confirmation and purification

Deliverable

The deliverable is a research cell bank (RCB). A GMP master cell bank (MCB) and commercial manufacture are carried out through CDMO partners.

CRO cell line development is not available for online ordering. Per-project quotations and terms are handled by separate enquiry.